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show that overexpression of long-pentraxin 3 (PTX3) in mice inhibits the growth of FGF-dependent tumor models. Electronic address: marco.presta@unibs.it. 94(11):1359-67, Consigli, V., Guarienti, M., Bilo, F., Benassi, L., Depero, L.E., Bontempi, E., Presta, M. (2016) Evaluation of the Biotoxicity of Tree Wood Ashes in Zebrafish Embryos. : 2021/2022 Curr Pharm Des 2007;13:2025-44. However, limitations to anti-VEGF therapies may exist because of the local production of other proangiogenic factors that may cause resistance to anti-VEGF interventions. On the basis of pharmacophore modeling of PTX3-FGF2 interaction, they identify a small molecule that acts as an extracellular FGF trap and inhibits FGF- dependent tumor growth in mice. Studio Prof. Presta, Sezione di Patologia ed Immunologia Sperimentale, VI piano Edificio Polifunzionale, Dipartimento medicina Molecolare e Traslazionale. ); chiara.tobia@unibs.it (C.T. domenico.ribatti@uniba.it. By Giulio Olivero, Daniele Maiolo, Daria Leali, Stefania Federici, Laura E. Depero, Marco Presta, Stefania Mitola and Paolo Bergese Un team di ricercatori del Dipartimento di Medicina Molecolare e Traslazionale, coordinato dal prof. Marco Presta, ha identificato un enzima coinvolto nella crescita del melanoma.. (2)Department of Medical Biotechnology and Translational Medicine, University of Milano, Milan, Italy. Here, we demonstrate that the autocrine FGF/FGFR axis is essential for multiple myeloma cell survival and progression by protecting multiple myeloma cells from … ); stefania.mitola@unibs.it (S.M.) 2018, Primo Semestre, Docente: MARCO PRESTA, erogato in: HEALTH AND WEALTH (PIANO GENERALE) 2 CFU Search for more papers by this author. Vascular endothelial growth factor (VEGF) blockers have been developed for the treatment of proliferative diabetic retinopathy (PDR), the leading cause of visual impairments in the working-age population in the Western world. MARINO Marco; NIGRO Michele; SILEO Sesto Manuel; TORRACA Rosario . Department of Oncology. Carlo BonfantiProf. : +39-030-3717311 Abstract: Proliferative diabetic retinopathy (PDR), a major complication of diabetes mellitus, results from an inflammation-sustained interplay among endothelial cells, neurons, and glia. Your input has been emailed to ZFIN curators who may contact you if Journal of Cellular and Molecular Medicine. marco.presta@unibs.it. Telefono: +390303717311. Un team di ricercatori del Dipartimento di Medicina Molecolare e Traslazionale, coordinato dal prof. Marco Presta, ha identificato un enzima coinvolto nella crescita del melanoma.. This page presents the Governing Bodies of the Department. 10:1092, Zizioli, D., Mione, M., Varinelli, M., Malagola, M., Bernardi, S., Alghisi, E., Borsani, G., Finazzi, D., Monti, E., Presta, M., Russo, D. (2018) Zebrafish disease models in hematology: Highlights on biological and translational impact. Lymph node (LN) expansion during inflammation is essential to establish immune responses and relies on the development of blood and lymph vessels. On the basis of pharmacophore modeling of PTX3-FGF2 interaction, they identify a small molecule that acts as an Anno Accademico 2017/2018 Marco Presta*, Patrizia Dell’Era, Stefania Mitola, Emanuela Moroni, Roberto Ronca, Marco Rusnati Unit of General Pathology and Immunology, Department of Biomedical Sciences and Biotechnology, School of Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy … marco.presta@unibs.it. 4. ); Prof. Marco Presta. IRIS Institutional Research Information System - OPENBS Open Archive UniBS. Nature Protocols. Ruolo: Professore Ordinario Dipartimento: Medicina Molecolare e Traslazionale ... Fax: 030371.7747 E-mail: marco.presta@unibs.it. Anno Accademico 2020/2021. 21:47-59, Belleri, M., Presta, M. (2016) Endothelial cell dysfunction in globoid cell leukodystrophy. Electronic address: silvano.sozzani@unibs.it. Received: 2 October 2020; Accepted: 19 November 2020; Published: 21 November 2020 Abstract: The chick embryo chorioallantoic membrane (CAM) represents a powerful in vivo model to study several physiological and pathological processes including inflammation and … Molecular basis of disease. Prof. Anna Maria Caroli SDS: AGR/17 – LIVESTOCK SYSTEMS, ANIMAL BREEDING AND … Molecular basis of disease. University of Torino-Italy Email verificata su unito.it. angiogenesi cancro endotelio zebrafish. Ricevimento. Electronic address: chiara.tobia@unibs.it. Running title: K5 derivative for diabetic retinopathy therapy Word count: 3993 Number images and tables: 6 figures and 2 tables Page 1 of 34 Diabetes Correspondence to: Marco Presta, email: marco.presta@unibs.it Keywords: angiogenesis, FGF8, hormone-regulated cancer, pentraxin, peptide Received: February 02, 2015 Accepted: March 26, 2015 Published: April 14, 2015 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any … Prof. Paolo Arosio SDS: BIO/11 – MOLECULAR BIOLOGY (Biology area) Email: paolo.arosio@unibs.it Telephone: +39 030/3717303. Marina PizziSDS: BIO/14 - PHARMACOLOGY (Biology area)Email: marina.pizzi@unibs.itTelephone: +39 030 3717501, ICT (Information and Communication Technology)Prof. Stefano CalzaSDS: MED/01 – MEDICAL STATISTICS (Medicine  area)Email: stefano.calza@unibs.itTelephone: +39 030 3717713URL: www.med.unibs.it/~calza, Members of the Research Quality Assurance Unit, Prof. Paolo ArosioProf. Fibroblast growth factors (FGF) act as proangiogenic and mitogenic cytokines in multiple myeloma. Marina ColombiProf. For the sustainable reuse of these materials is necessary to reduce the resulting impact on human health and environment. Correspondence to: Marco Presta, Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy. Journal of neuroscience research. Marco Presta Proliferative diabetic retinopathy (PDR), a major complication of diabetes mellitus, results from an inflammation-sustained interplay among endothelial cells, neurons, and glia. 80(22):5011-5023. 12(7): Ronca, R., Ghedini, G.C., Maccarinelli, F., Sacco, A., Locatelli, S.L., Foglio, E., Taranto, S., Grillo, E., Matarazzo, S., Castelli, R., Paganini, G., Desantis, V., Cattane, N., Cattaneo, A., Mor, M., Carlo-Stella, C., Belotti, A., Roccaro, A.M., Presta, M., Giacomini, A. Please check the highlighted fields and try again. E‐mail: marco.presta@unibs.it Search for more papers by this author additional information is required. Search for more papers by this author 0303717.311 - 0303717.225; mail: marco.presta@unibs.it; 2) Prof. Antonio Sica, Università degli Studi del Piemonte Orientale “Amedeo Avogadro” – Vercelli, Dipartimento di Scienze del Farmaco, Tel. E-mail address: marco.presta@unibs.it. Avviso di selezione per il conferimento di n. 1 borsa di ricerca - durata 7 mesi ref. marco.righi@in.cnr.it. E‐mail: marco.presta@unibs.it. Multiple myeloma, the second most common hematologic malignancy, frequently relapses because of chemotherapeutic resistance. Journal of hazardous materials. marco.presta@unibs.it (M.P.) Head: Prof. Marco Presta, Professor for the scientific and disciplinary sector MED/04 – GENERAL PATHOLOGY (Medicine area) Email: marco.presta@unibs.it Telephone: +39 030 3717311 Department (name and address) Department of Molecular and Translat ional Medicine Viale Europ a 11, 25123, Brescia, Italy 3. Correspondence to: Marco Presta, Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy. Rusnati M, Presta M. Fibroblast growth factors/fibroblast growth factor receptors as targets for the development of anti-angiogenesis strategies. E‐mail: marco.presta@unibs.it 8 Department of Basic Medical Sciences, Neurosciences and Sensory Organs, Section of Human Anatomy and Histology, University of Bari Medical School Bari, P.zza Giulio Cesare 11, 70124 Bari, Italy. Prof. Marco Presta SDS: MED/04 – GENERAL PATHOLOGY (Medicine area) Email: marco.presta@unibs.it Telephone: +39 030 3717311. Marco PrestaProf. Cancers. 4. DMMT-sede Europa. Sede di lavoro. Viale Europa, 11 Brescia . marco.presta@unibs.it. Studio Prof. Presta, Sezione di Patologia ed Immunologia Sperimentale, VI piano Edificio Polifunzionale, Dipartimento medicina Molecolare e Traslazionale Courses A.Y. Federico Bussolino Full Professor of Biochemistry. University of Torino-Italy Verified email at unito.it. Marco Presta UNIBS Massimo Santoro UNITO Paolo Sordino SZN A. Dohrn Stefania Fantino TECNIPLAST Comitato Locale: Natascia Tiso UNIPD Andrea Vettori UNIPD Segreteria Organizzativa Cecilia Zattara Daniela Rosin Maria Manno Giuseppe Cortese KINDLY SUPPORTED by PROGRAMMA February 2nd 2017 Registration: 8.00-9.15 Welcome: 9.15 1st Morning session 9.30-11.00 Chairperson … 0321375881; mail: ); Tel. Mitola, Efrem Foglia, Pieter B. van Loenen, Astrid E. Alewijnse and Marco Presta Chiara Tobia, Paola Chiodelli, Stefania Nicoli, Patrizia Dell'Era, Simone Buraschi, Stefania Zebrafish Sphingosine-1-Phosphate Receptor-1 Controls Venous Endothelial Barrier Integrity in Print ISSN: 1079-5642. 1862(7):1291-6, Liekens, S., Noppen, S., Gijsbers, S., Sienaert, R., Ronca, R., Tobia, C., Presta, M. (2015) The broad-spectrum anti-DNA virus agent cidofovir inhibits lung metastasis of virus-independent, FGF2-driven tumors. Anno Accademico 2018/2019. Roberto Ronca University of Brescia Email verificata su unibs.it. Settore scientifico-disciplinare di appartenenza: MED/04 PATOLOGIA GENERALE. Mariacristina MissaleProf. ); marco.presta@unibs.it (M.P. 7 Department of Molecular and Translational Medicine, University of Brescia, V.le Europa, 11, 25123 Brescia, Italy. N-formyl peptide receptors (FPRs) are G protein-coupled receptors involved in the recruitment and activation of immune cells in response to pathogen-associated molecular patterns. Informazioni. School of Medicine, University of Brescia Lo studio, che ha visto … 1832(9):1371-7, Tobia, C., Chiodelli, P., Nicoli, S., Dell'era, P., Buraschi, S., Mitola, S., Foglia, E., van Loenen, P.B., Alewijnse, A.E., and Presta, M. (2012) Sphingosine-1-Phosphate Receptor-1 Controls Venous Endothelial Barrier Integrity in Zebrafish. 4 Unit of Experimental Oncology and Immunology, Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy. Presta M, Camozzi M, Salvatori G, Rusnati M. Role of the soluble pattern recognition receptor PTX3 in vascular biology. 80:2340-2354. (3)Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy. Please try again later. *Correspondence: marco.presta@unibs.it; arianna.giacomini@unibs.it Running title: FGF blockade triggers MM oxidative stress Text word count: 3988 Abstract word count: 244 Number of figures: 7 Number of tables: 1 Number of references: 70 Scientific category: Lymphoid neoplasia. (8)Department of Basic Medical Sciences, Neurosciences and Sensory Organs, Section of Human Anatomy and Histology, University of Bari Medical School Bari, P.zza Giulio Cesare 11, 70124 Bari, Italy. Rezzola, S., Ronca, R., Loda, A., Nawaz, M.I., Tobia, C., Paganini, G., Maccarinelli, F., Giacomini, A., Semeraro, F., Mor, M., Presta, M. (2019) The Autocrine FGF/FGFR System in both Skin and Uveal Melanoma: FGF Trapping as a Possible Therapeutic Approach. Department of Biomedical Sciences and Biotechnology Zebrafish International Resource Center (ZIRC), European Zebrafish Resource Center (EZRC), Belleri, M., Paganini, G., Coltrini, D., Ronca, R., Zizioli, D., Corsini, M., Barbieri, A., Grillo, E., Calza, S., Bresciani, R., Maiorano, E., Mastropasqua, M.G., Annese, T., Giacomini, A., Ribatti, D., Casas, J., Levade, T., Fabrias, G., Presta, M. (2020) BETA-GALACTOSYLCERAMIDASE PROMOTES MELANOMA GROWTH VIA MODULATION OF CERAMIDE METABOLISM. Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy. Corsi. Diabetic retinopathy (DR) is one of the leading causes of visual impairment in the working-age population. viale Europa 11, 25123 Brescia, Italy. Viale Europa, 11 Brescia. Guerra, J., Chiodelli, P., Tobia, C., Gerri, C., Presta, M. (2020) Long-Pentraxin 3 Affects Primary Cilium in Zebrafish Embryo and Cancer Cells via the FGF System. 1) Prof. Marco Presta, Università degli Studi di Brescia, Dipartimento di Medicina Molecolare e Traslazionale, Tel. Marco PRESTA, born on June 21, 1954, Italy; Italian; 1977: PhD in Biological Sciences, University of Milan, Italy; 1984-86: Research Fellow, School of Medicine, N.Y.U. Email verificata su med.unibs.it. FGF blockade triggers MM oxidative stress 2 KEY POINTS Autocrine FGF signaling protects MM cells from oxidative … Arterioscler. Thromb. Angiogenesis. Biochimica et biophysica acta. Head of the Animal Breeding Department and Animal Welfare. cancers Article Long-Pentraxin 3 A ects Primary Cilium in Zebrafish Embryo and Cancer Cells via the FGF System Jessica Guerra 1,y, Paola Chiodelli 1,y, Chiara Tobia 1, Claudia Gerri 1,2 and Marco Presta 1,3,* 1 Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy; j.guerra@unibs.it (J.G. J Cell Mol Med 2007;11:723-38. (2011) The natural compound n-butylidenephthalide derived from the volatile oil of Radix Angelica sinensis inhibits angiogenesis in vitro and in vivo. Biochimica et biophysica acta. marco.presta@unibs.it. 9 Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy. Electronic address: marco.presta@unibs.it. 3 Unit of Experimental Oncology and Immunology, Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy. Roberto Ronca University of Brescia Verified email at unibs.it. (4)Department of Molecular and Translational Medicine, University of Brescia, viale Europa 11, 25123, Brescia, Italy. Un team di ricercatori del Dipartimento di Medicina Molecolare e Traslazionale, coordinato dal prof. Marco Presta, ha identificato un enzima coinvolto nella crescita del melanoma. IRIS è la piattaforma di gestione dei dati della ricerca, sviluppata da CINECA, all'interno della quale è integrato il nuovo catalogo dedicato alla raccolta e alla disseminazione della produzione scientifica dell'Università degli Studi di Brescia, denominato OPENBS. Joint Board. Prof. Anna Maria Caroli 14(2):187-97, Tobia, C., De Sena, G., and Presta, M. (2011) Zebrafish embryo, a tool to study tumor angiogenesis. * Correspondence: sara.rezzola@unibs.it (S.R. v.le Europa, 11 . +39 030 3717563 daniela.zizioli@unibs.it. Correspondence to: Marco Presta, Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy. vai al sito. 1842(4):665-675, Tobia, C., Gariano, G., Sena, G.D., and Presta, M. (2013) Zebrafish embryo as a tool to study tumor/endothelial cell cross-talk. ); marco.presta@unibs.it (M.P.) (3)Department of Oncology and Hematology, Humanitas Cancer Center, … Presta M, Camozzi M, Salvatori G, Rusnati M. Role of the soluble pattern recognition receptor PTX3 in vascular biology. Thank you for submitting comments. Calendario delle Sedute di Laurea Le sedute di laurea dell'A.A 2018-2019 si svolgeranno nelle seguenti date. 214:713-721, Rezzola, S., Paganini, G., Semeraro, F., Presta, M., Tobia, C. (2016) Zebrafish (Danio rerio) embryo as a platform for the identification of novel angiogenesis inhibitors of retinal vascular diseases. Department of Oncology. Mitola, Efrem Foglia, Pieter B. van Loenen, Astrid E. Alewijnse and Marco Presta Chiara Tobia, Paola Chiodelli, Stefania Nicoli, Patrizia Dell'Era, Simone Buraschi, Stefania Zebrafish Sphingosine-1-Phosphate Receptor-1 Controls Venous Endothelial Barrier Integrity in Print ISSN: 1079-5642. Fibroblast growth factors (FGF) act as proangiogenic and … Federico Bussolino Full Professor of Biochemistry. (4)Department of Molecular and Translational Medicine, University of Brescia, viale Europa 11, 25123, Brescia, Italy. marco presta professore ordinario in patologia generale Email verificata su med.unibs.it. * Correspondence: marco.presta@unibs.it y The two authors contributed equally to this work. (2020) FGF Trapping Inhibits Multiple Myeloma Growth through c-Myc Degradation-Induced Mitochondrial Oxidative Stress. Molecular basis of disease. Ordina per citazioni Ordina per anno Ordina per titolo. Joint Board. : +39‐03 03 71 73 11; Fax: +39‐03 03 70 11 57 E‐mail: presta@med.unibs.it. marco.presta@unibs.it. Ordina. Un team di ricercatori del Dipartimento di Medicina Molecolare e Traslazionale, coordinato dal prof. Marco Presta, ha identificato un enzima coinvolto nella crescita del melanoma. Author information: (1)CNR - Institute of Neuroscience, Milan, Italy. *Correspondence: marco.presta@unibs.it; arianna.giacomini@unibs.it Running title: FGF blockade triggers MM oxidative stress Text word count: 3988 Abstract word count: 244 Number of figures: 7 Number of tables: 1 Number of references: 70 Scientific category: Lymphoid neoplasia Molecular basis of disease. 12 Department of Biomedical Sciences and Biotechnology, University of Brescia marco.presta@unibs.it. Received: 9 June 2020; Accepted: 29 June 2020; Published: 1 July 2020 Abstract: Primary cilium drives the left-right asymmetry process during embryonic development. Corresponding Author: Marco Presta, Department of Molecular and Translational Medicine, School of Medicine, Viale Europa 11, 25123 Bres-cia, Italy. Correspondence to: Marco Presta, Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy. Zebrafish. Rusnati M, Presta M. Fibroblast growth factors/fibroblast growth factor receptors as targets for the development of anti-angiogenesis strategies. 1214:173-84, Guarienti, M., Gianoncelli, A., Bontempi, E., Moscoso Cardozo, S., Borgese, L., Zizioli, D., Mitola, S., Depero, L.E., Presta, M. (2014) Biosafe inertization of municipal solid waste incinerator residues by COSMOS technology.

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